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DOI:10.1002/14651858.CD008367.pub4 - Corpus ID: 229689987
@article{Zhao2020OralHC, title={Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia.}, author={Tingting Zhao and Xinyu Wu and Qi Zhang and Chunjie Li and Helen V Worthington and Fang Hua}, journal={The Cochrane database of systematic reviews}, year={2020}, volume={12}, pages={ CD008367 }, url={https://api.semanticscholar.org/CorpusID:229689987}}
- T. Zhao, Xinyu Wu, F. Hua
- Published in Cochrane Database of… 24 December 2020
- Medicine
Moderate-certainty evidence from 13 RCTs shows that CHX mouthrinse or gel, as part of OHC, probably reduces the incidence of VAP compared to placebo or usual care, which shows that providing OHC including CHX for 12 ventilated patients in intensive care would prevent one patient developing VAP.
35 Citations
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35 Citations
- Jennifer S Carroll SimmonsAnnette M BourgaultM. SoleB. Peach
- 2024
Medicine
Critical care nurse
The evidence regarding the efficacy of chlorhexidine gluconate oral care in reducing ventilator-associated events in specific intensive care unit populations is contradictory and may be beneficial only in the cardiac surgical population.
- 1
- Ma-I ChoiSun-Young Han So-Jung Mun
- 2022
Medicine
British Dental Journal
A model in which different health care professionals can cooperate to reduce the incidence of VAP and improve oral health conditions is suggested.
- 6
- T. BezerraClarissa Sales de Paula Campêlo F. Sousa
- 2020
Medicine
Although a reduction in the number of admissions or complexity of cases was not observed in the study period, multidisciplinary staff practices were essential for controllingHAIs and the presence of dental professionals can assist in the control of HAIs related to MV.
- Shaimaa Ahmed AliNourah AlsadaanM. AmeerMohamed Z. Sayed-AhmedF. Alanazi
- 2024
Medicine
Journal of medicine and life
The study revealed that CHX has a more powerful effect than HEX and NS in improving the oral mucosa and decreasing colonization of both the oropharynx and trachea, and recommends the use of a CHX solution as oral mouth care in critically ill patients.
- PDF
- C. DaleL. Rose B. Cuthbertson
- 2021
Medicine
Intensive Care Medicine
Among mechanically ventilated ICU patients, no benefit was observed for de-adoption of chlorhexidine and implementation of an oral care bundle on ICU mortality, IVACs, oral procedural pain, or time to extubation, but the intervention may improve oral health.
- 49
- PDF
- Canan KAŞ GÜNERS. Kutlutürkan
- 2021
Medicine
Medical Journal of Western Black Sea
It is thought that the methods applied to eliminate the risk of ventilator-associated pneumonia and nursing practices will contribute to direct the care practices of the staff in charge and affect the patient care results positively.
- 1
- PDF
- S. LavigneJ. Forrest
- 2020
Medicine, Environmental Science
Canadian journal of dental hygiene : CJDH…
Bradford Hill criteria analysis failed to support a causal relationship between periodontal microbes/oral health care and respiratory diseases such as pneumonia.
- 15
- PDF
- Laurent JadotL. Huyghens P. Damas
- 2018
Medicine
Annals of Intensive Care
Although a causal relationship cannot be inferred from these data, the successive surveys revealed a potential impact of the VAP bundle campaign on both the respiratory care of ventilated patients and the prevalence of VAP in Belgian ICUs encouraging them to follow the guidelines.
- 27
- PDF
- Akira ImakiireS. Soutome Masahiro Umeda
- 2024
Medicine
Cureus
Results indicate that topical PV-I application reduces the number of bacteria entering the lower respiratory tract and may help prevent VAP.
- PDF
- Yong XiangXiaolin RenYe XuLi ChengHe CaiT. Hu
- 2022
Medicine
International journal of environmental research…
To evaluate the anti-inflammatory and anti-bacterial effects of mouthwashes for critical care patients, the PubMed, EMBASE, CENTRAL, and grey literature databases were searched by descriptors combining population and intervention (mouthwashes).
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130 References
- F. HuaHuixu XieH. WorthingtonS. FurnessQi ZhangChunjie Li
- 2016
Medicine
The Cochrane database of systematic reviews
High quality evidence from 18 RCTs shows that CHX mouthrinse or gel, as part of OHC, reduces the risk of VAP compared to placebo or usual care, which is equivalent to a number needed to treat for an additional beneficial outcome (NNTB) of 17, which indicates that for every 17 ventilated patients in intensive care receiving OHC including chlorhexidine, one outcome of V AP would be prevented.
- 480
- PDF
- Zongdao ShiHuixu Xie S. Furness
- 2013
Medicine
The Cochrane database of systematic reviews
There is moderate quality evidence that CHX mouthrinse or gel, as part of OHC, compared to placebo or usual care is associated with a reduction in VAP, but there was insufficient evidence to determine whether there is a difference between CHX and placebo/usual care in the outcomes of mortality.
- 17
- PDF
- A. BerryP. DavidsonJ. MastersK. Rolls
- 2007
Medicine
American journal of critical care : an official…
The peer-reviewed literature was appraised to determine the best available evidence for providing oral care to intensive care patients receiving mechanical ventilation and to document a research agenda for this important activity in optimizing patients' outcomes.
- 164
- L. Fields
- 2008
Medicine
The Journal of neuroscience nursing : journal of…
This project specifically addressed timed oral care of mechanically ventilated patients on a 24‐bed stroke, neurologic, and medical ICU to support the premise that oral care, including timed toothbrushing, combined with the VAP bundle can mitigate and prevent the occurrence of VAP.
- 130
- PDF
- A. PoboT. Lisboa J. Rello
- 2009
Medicine
Chest
The findings suggest that the addition of electric toothbrushing to standard oral care with 0.12% chlorhexidine digluconate is not effective for the prevention of VAP.
- 124
- C. MunroM. J. GrapDeborah J. JonesD. McClishC. Sessler
- 2009
Medicine
American journal of critical care : an official…
Chlorhexidine, but not toothbrushing, reduced early ventilator-associated pneumonia in patients without pneumonia at baseline, and chlorhexidine significantly reduced the incidence of pneumonia on day 3 among patients who had CPIS <6 at baseline.
- 257
- PDF
- L. YaoCheng-Kuei ChangS. MaaCharlotte WangCheryl C-H Chen
- 2011
Medicine
The journal of nursing research : JNR
Findings suggest that, as an inexpensive alternative to existing protocols, toothbrushing twice daily with purified water reduces VAP and improves oral health and hygiene.
- 53
- PDF
- A. BerryA. BerryPatricia M. DavidsonJanet MastersK. RollsR. Ollerton
- 2011
Medicine
International journal of nursing studies
- 76
- A. Roca BioscaL. Anguera SaperasN. García GrauL. Rubio RicoM. C. Velasco Guillén
- 2011
Medicine
Enfermeria intensiva
- 15
- M. BuckleyA. DzierbaPamela L. SmithburgerK. McAllenChé J. JordanS. Kane‐Gill
- 2013
Medicine
Mixed results were shown and the majority failed to demonstrate a significant reduction in the incidence of nosocomial pneumonia with the use of chlorhexidine, however, the cardiothoracic surgery ICU patient population may benefit from its use.
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